XALOC evolution
Evolution of of XALOC in pictures from a project to reality
Beamline infrastructure was mostly installed in first half 2009. The main optical elements, namely the monochromator and the Horizontal and Vertical Focusing Mirrors (HFM and VFM), were set up in June 2009, whereas rest of the optics was completed later (Slits and XBPMs: October 2009; Shutter: May 2010; Fluo screens and white beam attenuator: fall 2010). The Experimental Station started assembly in Summer 2010, and was completed in July 2011. The detector was received and integrated at the beamline in May 2011. In-vacuum Undulator was installed in Summer 2011. XALOC started user operation on 18 July 2012
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14 Jan 2009 Hutches are being installed
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23 Feb 2009 (view from the bridge) Hutches and pillar structures have been painted |
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23 Feb 2009 (outboard side wall) Hutches and pillar structures have been painted |
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20 Mar 2009 (view from the bridge) Trays, PSS and electrical installations are in progress |
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21 May 2009 (view from the bridge) Fluid pipes installation is in progress. Optics to come soon! |
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21 May 2009 (outboard side wall) PSS and electrical installations are done. Optics to come soon! |
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19 June 2009 Main optical elements have been installed! (from far to close) Monochromator, Vertical Focusing Mirror, and Horizontal Focusing Mirror. |
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18 March 2010 End station starts installation The diffractometer (md2m, white), the diffractometer table (blue) and the automatic sample changer (yellow) are already in place. |
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| 25 March 2011 General view of the XALOC beamline. and the Alba Experimental Hall Almost all cabling has been routed and racks are in place |
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End station 6 May 2011 (view of the inside of the Experimental Hutch) The detector table (red) is being assembled vessels of XALOC. Cabling to the diffractometer and diff table (blue) and the automatic sample changer (yellow) has been mostly installed. |
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End station 18 July 2011 (view of the inside of the Experimental Hutch) Pulatus 6M detector already integrated. Robot (yellow) and diffractometer also in place. |
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BL13 team celebrating First Beam in XALOC 18 October 2011 Most of the staff who have been working part time in BL13. From left to right, up-bottom. Left side: Y. Nikitin, R. Martín, C. Colldelram, J. Benach, F. Rey, J. Juanhuix. Right side: G. Cuní, A, Rubio, C. Pascual, J. Lidón, O. Matilla, X. Farina, A. Enrique. |
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First focused beam at sample 29 February 2012 First image of the beam at sample with slits accepting full beam. Beam size is ~50x15 um (HxV, Full Width at Half Maximum). |
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BL13 team celebrating First Focused Beam at Sample in XALOC 29 February 2012 Most of the staff who have been working part time in BL13. From left to right, up-bottom. I. Sics, F. Farré, A. Crisol, J.C. Martínez, S. Ferrer (up), J. Juanhuix (bottom), J. Benach, A. Enrique, G. Cuní, X. Farina, C. Colldelram.Note the new Control Hutch! |
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First beam at the Pilatus Detector 15 December 2011 First image of the beam at detector. It shows a power diffraction pattern produced by the-2mm thick granulated aluminum detector cover. |
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25 April 2012 First high quality complete dataset of a lysozyme crystal:exp time 1sec, 1deg oscillation Resolution 1.26A Overall Rsym:3.8% (90deg) Lowest resolution shell Rsym:2% |
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First solved ab initio structure 8 June 2012 First ab intio structure in XALOC: a protein-DNA complex solved by Se-Met SAD )360deg, 2.4A resolution).The experiment was a beamline test, as the structure was already solved (PDB ID 2VS8, courtesy G. Montoya): |
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First Users 18 July 2012 XALOC starts user operation with the group of M. Coll, from IBMB-CSIC. |
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Very first structure solved at user operation 18 July 2012 Structure of a herpesvirus nuclease - antiviral complex. Data collected at Xaloc on July 18th, 2012. (Bongarzone, S., Nadal, M. & Coll, M.) |
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Hg SAD 4 Dec 2012 Hg derivative (using PCMB, p-chloro-mercury-benzoate) of Sca-1, a C-type lectin type protein involved in biomineralization processes. Map was obtained without any refinement.(A. Romero, CIB-CSIC) |
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First High-impact publication with XALOC data 21 Feb 2014 The 3D structureshave revealed why a given Auxin Response Factor (ARF, plant transcription factor) is capable of activating a single set of genes, while other ARFs that are very similar with only slight differences trigger a distinct set (R. Boer, M. Coll, et al. Cell, 2014 156:577) |
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